Acute generalized exanthematous pustulosis - Pachimake Generalized Exanthematous Pustulosis
Pachimake Generalized Exanthematous Pustulosis (Acute generalized exanthematous pustulosis) (AGEP) ndizovuta zapakhungu zomwe mu 90% ya milandu zimakhudzana ndi kuwongolera mankhwala. pachimake generalized exanthematous pustulosis (acute generalized exanthematous pustulosis) imadziwika ndi kuphulika kwadzidzidzi kwapakhungu komwe kumachitika pafupifupi masiku asanu mutayamba kumwa mankhwala. Kuphulika kumeneku ndi pustules, mwachitsanzo, kuphulika kwakung'ono kofiira kofiira kapena kofiira kwa khungu komwe kumakhala ndi mitambo kapena purulent (mafinya). Zotupa pakhungu nthawi zambiri zimatha pakadutsa masiku 1-3 mutasiya kumwa mankhwala.
☆ Muzotsatira za 2022 Stiftung Warentest zochokera ku Germany, kukhutitsidwa kwa ogula ndi ModelDerm kunali kotsika pang'ono kusiyana ndi kuyankhulana kwa telemedicine komwe kulipiridwa.
Zilonda zofala ndi erythema ndi pustules zimawonekera mwadzidzidzi.
References
Acute generalized exanthematous pustulosis (AGEP) ndi kachitidwe kakhungu komwe kamadziwika ndi tiziphuphu tating'ono, todzaza mafinya pakhungu lofiira. Nthawi zambiri zimachitika munthu akamamwa mankhwala enaake, monga maantibayotiki, ndikufalikira thupi lonse. Mukasiya kumwa mankhwalawo, zizindikirozo zimatha pakangotha milungu iwiri, ndipo nthawi zambiri zimasiya kukhetsa khungu. Ngakhale nthawi zambiri sizovuta komanso zochepera pakhungu, zowopsa zimatha kugawidwa pamodzi ndi zovuta zina zapakhungu monga Stevens-Johnson syndrome kapena toxic epidermal necrolysis. Chithandizo makamaka ndi chithandizo chothandizira, ndipo kuneneratu kuti matendawa athetsedwe nthawi zambiri amakhala abwino kwambiri.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Acute generalized exanthematous pustulosis (AGEP) is an adverse cutaneous reaction characterized by sterile pinpoint nonfollicular pustules atop an erythematous background. Symptoms most often occur in the setting of medication exposure, such as systemic antibiotics, rapidly become generalized, followed by desquamation and resolution within about two weeks of discontinuing the offending trigger. Although mostly self-limited without systemic involvement, severe cases are classified alongside other cutaneous adverse reactions such as Stevens-Johnson syndrome, toxic epidermal necrolysis, and drug reaction with eosinophilia and systemic symptoms. Treatment is primarily supportive, and the prognosis for complete resolution is excellent.
Recent experimental data reviewed herein are supportive of an early role of drug-induced innate immune activation and innate cytokines such as interleukin (IL)-1, IL-36, and IL-17 in the pathogenesis of AGEP. This explains the rapid onset and neutrophilic character of the cutaneous inflammation.
Bambo wina wazaka 76 anabwera kuchipinda chodzidzimutsa chifukwa khungu lake linali litasintha masiku awiri apitawa. Madokotala adapeza zigamba zofiira ndikukweza thunthu lake, mikono ndi miyendo yake. M'kupita kwa nthawi, zigambazi zinalumikizana, ndipo anayamba kukhala ngati ziphuphu m'madera ofiira. Mayeso adawonetsa kuchuluka kwa maselo oyera amwazi okhala ndi mitundu yambiri yotchedwa neutrophils, komanso kuchuluka kwa C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
A 76-year-old male patient presented as an emergency due to a 2-day history of skin changes. Physical examination revealed disseminated erythematous macules and plaques on the trunk and extremities. In the further course, confluence of the macules and non-follicular pustulosis developed in the area of erythema. Laboratory tests revealed leukocytosis with neutrophils and elevated C-reactive protein.
